Days supply in pharmacy: billing accuracy and refill timing
Days supply is the number of days a dispensed quantity will last at the prescribed dosing frequency. It determines when a patient can request a refill, drives insurance billing, and affects dispensing fee calculations for multi-month supplies. CMS publishes its own pharmacy billing job aid covering exactly this calculation for Medicaid claims.
Tablets and capsules: the straightforward formula
Days supply = quantity dispensed / (dose per administration × doses per day). 90 tablets at 1 tablet twice daily = 90 / (1 × 2) = 45 days. 90 tablets at 2 tablets once daily = 90 / (2 × 1) = 45 days. The formula is symmetric, what matters is total tablets consumed per day. Once you know the days supply, our Refill Reminder and Tracker can calculate the exact date to request your next fill.
Eye drops: the most commonly miscalculated
Eye drop days supply requires knowing drops per mL (typically 20 for standard ophthalmic drops, but varies by viscosity), the number of drops per dose and how many eyes are treated. A 5mL bottle at 20 drops/mL = 100 drops total. If dosing is 1 drop in each eye twice daily = 4 drops per day. Days supply = 100 / 4 = 25 days. Many billing rejections come from incorrect eye drop days supply. If a product's labelling gives drop count in an unfamiliar unit, our Pharmacy Unit Converter can help translate it into mL before you calculate.
Insulin: units per package matter
A standard U-100 10mL vial contains 1000 units. A standard U-100 pen cartridge (3mL) contains 300 units. Toujeo is U-300, 3 pens contain 900 units. At 20 units daily: 3 standard pens = 900/20 = 45 days. Getting insulin days supply wrong is one of the most common pharmacy billing errors. Whatever the days-supply figure, a fundamental dispensing rule sits alongside it: FDA safety communications require insulin pens to carry a "for single patient use only" warning, since sharing a pen between patients, even with a fresh needle each time, risks transmitting bloodborne infections. Pair this with our SIG Code Decoder to confirm dosing instructions before calculating, and the NDC Lookup for accurate package quantity verification.